Association of ADAM33 Gene Polymorphisms with Keloid Scars in a Northeastern Chinese Population

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Association of ADAM33 gene polymorphisms with keloid scars in a northeastern Chinese population.

OBJECTIVE To study the association between ADAM33 and keloid scars in the northeastern Chinese population. METHODS A total of 283 keloid scar patients and a control group of 290 healthy volunteers were recruited for this study. Six polymorphic loci (V4, T+1, T2, T1, S2 and Q-1 ) of ADAM33 were selected for genotyping. Genotypes were determined by using the polymerase chain reaction-restrictio...

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Association of ADAM33 gene polymorphisms with allergic asthma

Objective(s): Asthma results from the interaction between genetic and environmental factors. ADAM33 gene on chromosome 20p13 is associated with asthma and airway hyperresponsiveness. Materials and Methods: This is a case-control study, where four SNPs S1 (rs3918396), T1 (rs2280091), T2 (rs2280090), V4 (rs2787094) of ADAM33 gene have been assessed in patients with allergic asthma and normal con...

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ADAM33 gene polymorphisms in Southwestern Iranian patients with asthma

Objective(s): Asthma, the most frequent chronic respiratory disease, results from a complex interaction between multiple genes and environmental factors. To date, more than 100 candidate genes and single nucleotide polymorphisms (SNPs) have been reported to be associated with asthma. One of the discovered genes related to asthma is ADAM33. However, the relationship between ADAM33 gene polymorph...

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Polymorphisms of prolactin gene in a native chicken population and its association with egg production

The induction and regulation of broodiness is of the most important role of prolactin in avian species.The promoter region of the prolactin gene is an appropriate model for studying tissue-specific andhormonally-regulated activation of gene transcription. In this study, the association between prolactinpromoter region alleles and egg production in Fars native chickens was investigated. In total...

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ژورنال

عنوان ژورنال: Cellular Physiology and Biochemistry

سال: 2014

ISSN: 1015-8987,1421-9778

DOI: 10.1159/000366314